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Tumor-Stroma Crosstalk in Bone Tissue: The Osteoclastogenic Potential of a Breast Cancer Cell Line in a Co-Culture System and the Role of EGFR Inhibition
Although bone metastases represent a major challenge in the natural history of breast cancer (BC), the complex interactions involved have hindered the development of robust in vitro models. The aim of this work is the development of a preclinical model of cancer and bone stromal cells to mimic the b...
Autores principales: | Mercatali, Laura, La Manna, Federico, Miserocchi, Giacomo, Liverani, Chiara, De Vita, Alessandro, Spadazzi, Chiara, Bongiovanni, Alberto, Recine, Federica, Amadori, Dino, Ghetti, Martina, Ibrahim, Toni |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578045/ https://www.ncbi.nlm.nih.gov/pubmed/28758931 http://dx.doi.org/10.3390/ijms18081655 |
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