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Nrf2-Knockout Protects from Intestinal Injuries in C57BL/6J Mice Following Abdominal Irradiation with γ Rays

Radiation-induced intestinal injuries (RIII) commonly occur in patients who suffer from pelvic or abdominal cancer. Nuclear factor-erythroid 2-related factor 2 (Nrf2) is a key transcriptional regulator of antioxidant, and the radioprotective role of Nrf2 is found in bone marrow, lung, and intestine,...

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Detalles Bibliográficos
Autores principales: Yang, Wenyan, Sun, Zhijuan, Yang, Bing, Wang, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578046/
https://www.ncbi.nlm.nih.gov/pubmed/28758961
http://dx.doi.org/10.3390/ijms18081656