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Polycomb Repressor Complex 2 in Genomic Instability and Cancer

Polycomb repressor complexes PRC1 and PRC2 regulate chromatin compaction and gene expression, and are widely recognized for their fundamental contributions to developmental processes. Herein, we summarize the existing evidence and molecular mechanisms linking PRC-mediated epigenetic aberrations to g...

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Detalles Bibliográficos
Autores principales: Veneti, Zoe, Gkouskou, Kalliopi K., Eliopoulos, Aristides G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578047/
https://www.ncbi.nlm.nih.gov/pubmed/28758948
http://dx.doi.org/10.3390/ijms18081657