Cargando…

Polycomb Repressor Complex 2 in Genomic Instability and Cancer

Polycomb repressor complexes PRC1 and PRC2 regulate chromatin compaction and gene expression, and are widely recognized for their fundamental contributions to developmental processes. Herein, we summarize the existing evidence and molecular mechanisms linking PRC-mediated epigenetic aberrations to g...

Descripción completa

Detalles Bibliográficos
Autores principales:	Veneti, Zoe, Gkouskou, Kalliopi K., Eliopoulos, Aristides G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578047/ https://www.ncbi.nlm.nih.gov/pubmed/28758948 http://dx.doi.org/10.3390/ijms18081657

Ejemplares similares

Genetically Guided Mediterranean Diet for the Personalized Nutritional Management of Type 2 Diabetes Mellitus
por: Gkouskou, Kalliopi, et al.
Publicado: (2021)

The gut microbiota in mouse models of inflammatory bowel disease
por: Gkouskou, Kalliopi K., et al.
Publicado: (2014)

SUMOylation Is Required for Optimal TRAF3 Signaling Capacity
por: Miliara, Sophia, et al.
Publicado: (2013)

Polycomb repressor complex 2 function in breast cancer (Review)
por: Martin, Courtney J., et al.
Publicado: (2020)

Structural heterogeneity of the mammalian polycomb repressor complex in immune regulation
por: Kang, Seok-Jin, et al.
Publicado: (2020)

COVID-19 enters the expanding network of apolipoprotein E4-related pathologies
por: Gkouskou, Kalliopi, et al.
Publicado: (2021)

Genetically-Guided Medical Nutrition Therapy in Type 2 Diabetes Mellitus and Pre-diabetes: A Series of n-of-1 Superiority Trials
por: Gkouskou, Kalliopi K., et al.
Publicado: (2022)

REST–Mediated Recruitment of Polycomb Repressor Complexes in Mammalian Cells
por: Dietrich, Nikolaj, et al.
Publicado: (2012)

Deregulation of polycomb repressor complex 1 modifier AUTS2 in T-cell leukemia
por: Nagel, Stefan, et al.
Publicado: (2016)

Selective requirement for polycomb repressor complex 2 in the generation of specific hypothalamic neuronal subtypes
por: Yaghmaeian Salmani, Behzad, et al.
Publicado: (2022)

Obsessed with Healthy Eating: A Systematic Review of Observational Studies Assessing Orthorexia Nervosa in Patients with Diabetes Mellitus
por: Grammatikopoulou, Maria G., et al.
Publicado: (2021)

Survivin prevents the polycomb repressor complex 2 from methylating histone 3 lysine 27
por: Jensen, Maja, et al.
Publicado: (2023)

Chromatin Sampling—An Emerging Perspective on Targeting Polycomb Repressor Proteins
por: Klose, Robert J., et al.
Publicado: (2013)

Polycomb repressor complex 2 regulates HOXA9 and HOXA10, activating ID2 in NK/T-cell lines
por: Nagel, Stefan, et al.
Publicado: (2010)

The transcriptional repressors VAL1 and VAL2 recruit PRC2 for genome-wide Polycomb silencing in Arabidopsis
por: Yuan, Liangbing, et al.
Publicado: (2020)

Structural basis for targeting the chromatin repressor Sfmbt to Polycomb response elements
por: Alfieri, Claudio, et al.
Publicado: (2013)

Arabidopsis DNA polymerase ϵ recruits components of Polycomb repressor complex to mediate epigenetic gene silencing
por: del Olmo, Iván, et al.
Publicado: (2016)

Variational autoencoding of gene landscapes during mouse CNS development uncovers layered roles of Polycomb Repressor Complex 2
por: Mora, Ariane, et al.
Publicado: (2022)

Molecular recognition of histone lysine methylation by the Polycomb group repressor dSfmbt
por: Grimm, Clemens, et al.
Publicado: (2009)

Evolutionary adaptation of the Polycomb repressive complex 2
por: Fischer, Sabrina, et al.
Publicado: (2022)

Polycomb Repressor Complex 1 Member, BMI1 Contributes to Urothelial Tumorigenesis through p16-Independent Mechanisms()
por: De Faveri, Lia E., et al.
Publicado: (2015)

The Human Immunodeficiency Virus 1 ASP RNA promotes viral latency by recruiting the Polycomb Repressor Complex 2 and promoting nucleosome assembly
por: Zapata, Juan C., et al.
Publicado: (2017)

Polycomb repressor complex 2 suppresses interferon-responsive MHC-II expression in melanoma cells and is associated with anti-PD-1 resistance
por: James, Jamaal L, et al.
Publicado: (2023)

Critical Roles of Polycomb Repressive Complexes in Transcription and Cancer
por: Dong, Guan-Jun, et al.
Publicado: (2022)

Polycomb complexes in normal and malignant hematopoiesis
por: Di Carlo, Valerio, et al.
Publicado: (2019)

Polycomb Repressive Complex 2 in Eukaryotes—An Evolutionary Perspective
por: Vijayanathan, Mallika, et al.
Publicado: (2022)

Targeting polycomb repressor complex 2‐mediated bivalent promoter epigenetic silencing of secreted frizzled‐related protein 1 inhibits cholangiocarcinoma progression
por: Wu, Guanhua, et al.
Publicado: (2023)

Polycomb repressor complex 1 promotes gene silencing through H2AK119 mono-ubiquitination in acinar-to-ductal metaplasia and pancreatic cancer cells
por: Benitz, Simone, et al.
Publicado: (2015)

Molecular architecture of polycomb repressive complexes
por: Chittock, Emily C., et al.
Publicado: (2017)

Loss of polycomb repressive complex 1 activity and chromosomal instability drive uveal melanoma progression
por: Bakhoum, Mathieu F., et al.
Publicado: (2021)

Genome-wide activities of Polycomb complexes control pervasive transcription
por: Lee, Hun-Goo, et al.
Publicado: (2015)

The Challenge and Importance of Integrating Drug–Nutrient–Genome Interactions in Personalized Cardiovascular Healthcare
por: Stouras, Ioannis, et al.
Publicado: (2022)

The Importance of Networking: Plant Polycomb Repressive Complex 2 and Its Interactors
por: Godwin, James, et al.
Publicado: (2022)

Role of Polycomb Complexes in Normal and Malignant Plasma Cells
por: Varlet, Emmanuel, et al.
Publicado: (2020)

Constructing personalized longitudinal holo’omes of colon cancer-prone humans and their modeling in flies and mice
por: Panagi, Myrofora, et al.
Publicado: (2015)

Huntingtin facilitates polycomb repressive complex 2
por: Seong, Ihn Sik, et al.
Publicado: (2010)

Hierarchical recruitment of Polycomb complexes revisited
por: Dorafshan, Eshagh, et al.
Publicado: (2017)

Roles of Polycomb Complexes in the Reconstruction of 3D Genome Architecture during Preimplantation Embryonic Development
por: Yu, Longtao, et al.
Publicado: (2022)

The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis
por: Oliviero, Giorgio, et al.
Publicado: (2015)

TPL2-NPM-p53 pathway monitors nucleolar stress
por: Eliopoulos, Aristides G., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_olkbq7b5csphtk6arufkj4fed4