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Do Multiwell Plate High Throughput Assays Measure Loss of Cell Viability Following Exposure to Genotoxic Agents?

Cell-based assays in multiwell plates are widely used for radiosensitivity and chemosensitivity assessment with different mammalian cell types. Despite their relative ease of performance, such assays lack specificity as they do not distinguish between the cytostatic (reversible/sustained growth arre...

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Detalles Bibliográficos
Autores principales: Mirzayans, Razmik, Andrais, Bonnie, Murray, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578069/
https://www.ncbi.nlm.nih.gov/pubmed/28767065
http://dx.doi.org/10.3390/ijms18081679