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Electronegative Low-Density Lipoprotein L5 Impairs Viability and NGF-Induced Neuronal Differentiation of PC12 Cells via LOX-1

There have been striking associations of cardiovascular diseases (e.g., atherosclerosis) and hypercholesterolemia with increased risk of neurodegeneration including Alzheimer’s disease (AD). Low-density lipoprotein (LDL), a cardiovascular risk factor, plays a crucial role in AD pathogenesis; further...

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Detalles Bibliográficos
Autores principales: Wang, Jiz-Yuh, Lai, Chiou-Lian, Lee, Ching-Tien, Lin, Chen-Yen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578134/
https://www.ncbi.nlm.nih.gov/pubmed/28800073
http://dx.doi.org/10.3390/ijms18081744