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Endocytosis of Albumin Induces Matrix Metalloproteinase-9 by Activating the ERK Signaling Pathway in Renal Tubule Epithelial Cells

Matrix metalloproteinase-9 (MMP-9) is dysregulated in chronic kidney diseases including diabetic nephropathy. This study was performed to examine the expression of MMP-9 in renal tubule epithelial cells (TECs) under diabetic conditions and its regulatory mechanisms. We characterized MMP-9 protein in...

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Detalles Bibliográficos
Autores principales: Chen, Xiaoming, Cobbs, Alyssa, George, Jasmine, Chima, Ashmeer, Tuyishime, Fidele, Zhao, Xueying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578147/
https://www.ncbi.nlm.nih.gov/pubmed/28805677
http://dx.doi.org/10.3390/ijms18081758