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The Mechanistic Links between Insulin and Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Cl(−) Channel

The cystic fibrosis transmembrane conductance regulator (CFTR) Cl(−) channel belongs to the ATP-binding cassette (ABC) transporter superfamily and regulates Cl(−) secretion in epithelial cells for water secretion. Loss-of-function mutations to the CFTR gene cause dehydrated mucus on the apical side...

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Detalles Bibliográficos
Autor principal: Marunaka, Yoshinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578156/
https://www.ncbi.nlm.nih.gov/pubmed/28805732
http://dx.doi.org/10.3390/ijms18081767