Epigenome Aberrations: Emerging Driving Factors of the Clear Cell Renal Cell Carcinoma

Clear cell renal cell carcinoma (ccRCC), the most common form of Kidney cancer, is characterized by frequent mutations of the von Hippel-Lindau (VHL) tumor suppressor gene in ~85% of sporadic cases. Loss of pVHL function affects multiple cellular processes, among which the activation of hypoxia indu...

Descripción completa

Detalles Bibliográficos
Autores principales: Mehdi, Ali, Riazalhosseini, Yasser
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578163/
https://www.ncbi.nlm.nih.gov/pubmed/28812986
http://dx.doi.org/10.3390/ijms18081774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578163/
https://www.ncbi.nlm.nih.gov/pubmed/28812986
http://dx.doi.org/10.3390/ijms18081774

Ejemplares similares