Cargando…
Epigenome Aberrations: Emerging Driving Factors of the Clear Cell Renal Cell Carcinoma
Clear cell renal cell carcinoma (ccRCC), the most common form of Kidney cancer, is characterized by frequent mutations of the von Hippel-Lindau (VHL) tumor suppressor gene in ~85% of sporadic cases. Loss of pVHL function affects multiple cellular processes, among which the activation of hypoxia indu...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578163/ https://www.ncbi.nlm.nih.gov/pubmed/28812986 http://dx.doi.org/10.3390/ijms18081774 |