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Signaling Cascade Involved in Rapid Stimulation of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) by Dexamethasone

Impairment of mucociliary clearance with reduced airway fluid secretion leads to chronically inflamed airways. Cystic fibrosis transmembrane conductance regulator (CFTR) is crucially involved in airway fluid secretion and dexamethasone (dexa) has previously been shown to elevate CFTR activity in air...

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Detalles Bibliográficos
Autores principales: Bossmann, Miriam, Ackermann, Benjamin W., Thome, Ulrich H., Laube, Mandy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578194/
https://www.ncbi.nlm.nih.gov/pubmed/28825630
http://dx.doi.org/10.3390/ijms18081807