Cargando…
Genome-Wide RNAi Ionomics Screen Reveals New Genes and Regulation of Human Trace Element Metabolism
Trace elements are essential for human metabolism and dysregulation of their homeostasis is associated with numerous disorders. Here we characterize mechanisms that regulate trace elements in human cells by designing and performing a genome-wide high-throughput siRNA/ionomics screen, and examining t...
Autores principales: | Malinouski, Mikalai, Hasan, Nesrin M., Zhang, Yan, Seravalli, Javier, Lin, Jie, Avanesov, Andrei, Lutsenko, Svetlana, Gladyshev, Vadim N. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578452/ https://www.ncbi.nlm.nih.gov/pubmed/24522796 http://dx.doi.org/10.1038/ncomms4301 |
Ejemplares similares
-
Systematic age‐, organ‐, and diet‐associated ionome remodeling and the development of ionomic aging clocks
por: Zhang, Bohan, et al.
Publicado: (2020) -
Hydrogen Peroxide Probes Directed to Different Cellular Compartments
por: Malinouski, Mikalai, et al.
Publicado: (2011) -
Characterization of the yeast ionome: a genome-wide analysis of nutrient mineral and trace element homeostasis in Saccharomyces cerevisiae
por: Eide, David J, et al.
Publicado: (2005) -
Reduced reliance on the trace element selenium during evolution of mammals
por: Lobanov, Alexey V, et al.
Publicado: (2008) -
Macro and trace elements signature of periodontitis in saliva: A systematic review with quality assessment of ionomics studies
por: Baima, Giacomo, et al.
Publicado: (2021)