Cargando…

CD161 Expression on Mucosa-Associated Invariant T Cells is Reduced in HIV-Infected Subjects Undergoing Antiretroviral Therapy Who Do Not Recover CD4(+) T Cells

BACKGROUND: Mucosa-associated invariant T (MAIT) cells are a recently identified class of innate-like T cells that are involved in the mucosal immune response. MAIT cells are characterized by expression of TCR Vα7.2 and CD161. In HIV infection, there is a profound early loss of MAIT cells from the c...

Descripción completa

Detalles Bibliográficos
Autores principales: Freeman, Michael L., Morris, Stephen R., Lederman, Michael M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pathogens and Immunity 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578469/
https://www.ncbi.nlm.nih.gov/pubmed/28868514
http://dx.doi.org/10.20411/pai.v2i3.136