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Open chromatin profiling identifies AP1 as a transcriptional regulator in oesophageal adenocarcinoma

Oesophageal adenocarcinoma (OAC) is one of the ten most prevalent forms of cancer and is showing a rapid increase in incidence and yet exhibits poor survival rates. Compared to many other common cancers, the molecular changes that occur in this disease are relatively poorly understood. However, gene...

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Detalles Bibliográficos
Autores principales: Britton, Edward, Rogerson, Connor, Mehta, Shaveta, Li, Yaoyong, Li, Xiaodun, Fitzgerald, Rebecca C., Ang, Yeng S., Sharrocks, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578490/
https://www.ncbi.nlm.nih.gov/pubmed/28859074
http://dx.doi.org/10.1371/journal.pgen.1006879