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Directed evolution provides insight into conformational substrate sampling by SrtA

The Sortase family of transpeptidases are found in numerous gram-positive bacteria and involved in divergent physiological processes including anchoring of surface proteins to the cell wall as well as pili assembly. As essential proteins, sortase enzymes have been the focus of considerable interest...

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Detalles Bibliográficos
Autores principales: Suliman, Muna, Santosh, Vishaka, Seegar, Tom C. M., Dalton, Annamarie C., Schultz, Kathryn M., Klug, Candice S., Barton, William A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578623/
https://www.ncbi.nlm.nih.gov/pubmed/28859178
http://dx.doi.org/10.1371/journal.pone.0184271