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Distinct roles and differential expression levels of Wnt5a mRNA isoforms in colorectal cancer cells

The canonical Wnt/β-catenin pathway is constitutively activated in more than 90% of colorectal cancer (CRC) cases in which β-catenin contributes to CRC cell growth and survival. In contrast to the Wnt/β-catenin pathway, the non-canonical Wnt pathway can antagonize functions of the canonical Wnt/β-ca...

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Detalles Bibliográficos
Autores principales: Huang, Tsui-Chin, Lee, Pin-Tse, Wu, Ming-Heng, Huang, Chi-Chen, Ko, Chiung-Yuan, Lee, Yi-Chao, Lin, Ding-Yen, Cheng, Ya-Wen, Lee, Kuen-Haur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578641/
https://www.ncbi.nlm.nih.gov/pubmed/28859077
http://dx.doi.org/10.1371/journal.pone.0181034