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Obesity-associated metabolic syndrome spontaneously induces infiltration of pro-inflammatory macrophage in synovium and promotes osteoarthritis

OBJECTIVES: Epidemiological and experimental studies have established obesity to be an important risk factor for osteoarthritis (OA), however, the mechanisms underlying this link remains largely unknown. Here, we studied local inflammatory responses in metabolic-OA. METHODS: Wistar rats were fed wit...

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Detalles Bibliográficos
Autores principales: Sun, Antonia RuJia, Panchal, Sunil K., Friis, Thor, Sekar, Sunderajhan, Crawford, Ross, Brown, Lindsay, Xiao, Yin, Prasadam, Indira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578643/
https://www.ncbi.nlm.nih.gov/pubmed/28859108
http://dx.doi.org/10.1371/journal.pone.0183693