Cargando…
Obesity-associated metabolic syndrome spontaneously induces infiltration of pro-inflammatory macrophage in synovium and promotes osteoarthritis
OBJECTIVES: Epidemiological and experimental studies have established obesity to be an important risk factor for osteoarthritis (OA), however, the mechanisms underlying this link remains largely unknown. Here, we studied local inflammatory responses in metabolic-OA. METHODS: Wistar rats were fed wit...
Autores principales: | Sun, Antonia RuJia, Panchal, Sunil K., Friis, Thor, Sekar, Sunderajhan, Crawford, Ross, Brown, Lindsay, Xiao, Yin, Prasadam, Indira |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578643/ https://www.ncbi.nlm.nih.gov/pubmed/28859108 http://dx.doi.org/10.1371/journal.pone.0183693 |
Ejemplares similares
-
Saturated fatty acids induce development of both metabolic syndrome and osteoarthritis in rats
por: Sekar, Sunderajhan, et al.
Publicado: (2017) -
Dietary Saturated Fatty Acids Modulate Pain Behaviour in Trauma-Induced Osteoarthritis in Rats
por: Sekar, Sunderajhan, et al.
Publicado: (2020) -
Obesity, Inflammation, and Immune System in Osteoarthritis
por: Nedunchezhiyan, Udhaya, et al.
Publicado: (2022) -
Pro-resolving lipid mediator ameliorates obesity induced osteoarthritis by regulating synovial macrophage polarisation
por: Sun, Antonia Rujia, et al.
Publicado: (2019) -
Spatial distribution of elements during osteoarthritis disease progression using synchrotron X-ray fluorescence microscopy
por: Fan, Xiwei, et al.
Publicado: (2023)