Metabolic inhibition reduces cardiac L-type Ca(2+) channel current due to acidification caused by ATP hydrolysis

Metabolic stress evoked by myocardial ischemia leads to impairment of cardiac excitation and contractility. We studied the mechanisms by which metabolic inhibition affects the activity of L-type Ca(2+) channels (LTCCs) in frog ventricular myocytes. Metabolic inhibition induced by the protonophore FC...

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Detalles Bibliográficos
Autores principales: Kanaporis, Giedrius, Treinys, Rimantas, Fischmeister, Rodolphe, Jurevičius, Jonas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578678/
https://www.ncbi.nlm.nih.gov/pubmed/28859158
http://dx.doi.org/10.1371/journal.pone.0184246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578678/
https://www.ncbi.nlm.nih.gov/pubmed/28859158
http://dx.doi.org/10.1371/journal.pone.0184246

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