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Metabolic inhibition reduces cardiac L-type Ca(2+) channel current due to acidification caused by ATP hydrolysis
Metabolic stress evoked by myocardial ischemia leads to impairment of cardiac excitation and contractility. We studied the mechanisms by which metabolic inhibition affects the activity of L-type Ca(2+) channels (LTCCs) in frog ventricular myocytes. Metabolic inhibition induced by the protonophore FC...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578678/ https://www.ncbi.nlm.nih.gov/pubmed/28859158 http://dx.doi.org/10.1371/journal.pone.0184246 |