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Transient expression of ZBTB32 in anti-viral CD8(+) T cells limits the magnitude of the effector response and the generation of memory

Virus infections induce CD8(+) T cell responses comprised of a large population of terminal effector cells and a smaller subset of long-lived memory cells. The transcription factors regulating the relative expansion versus the long-term survival potential of anti-viral CD8(+) T cells are not complet...

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Detalles Bibliográficos
Autores principales: Shin, Hyun Mu, Kapoor, Varun N., Kim, Gwanghun, Li, Peng, Kim, Hang-Rae, Suresh, M., Kaech, Susan M., Wherry, E. John, Selin, Liisa K., Leonard, Warren J., Welsh, Raymond M., Berg, Leslie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578684/
https://www.ncbi.nlm.nih.gov/pubmed/28827827
http://dx.doi.org/10.1371/journal.ppat.1006544