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Pulling MscL open via N-terminal and TM1 helices: A computational study towards engineering an MscL nanovalve
There are great opportunities in the manipulation of bacterial mechanosensitive (MS) ion channels for specific and targeted drug delivery purposes. Recent research has shown that these ion channels have the potential to be converted into nanovalves through clever use of magnetic nanoparticles and ma...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578686/ https://www.ncbi.nlm.nih.gov/pubmed/28859093 http://dx.doi.org/10.1371/journal.pone.0183822 |