Two separate pathways regulate protein stability of ATM/ATR-related protein kinases Mec1 and Tel1 in budding yeast

Checkpoint signaling requires two conserved phosphatidylinositol 3-kinase-related protein kinases (PIKKs): ATM and ATR. In budding yeast, Tel1 and Mec1 correspond to ATM and ATR, respectively. The Tel2-Tti1-Tti2 (TTT) complex connects to the Rvb1-Rvb2-Tah1-Pih1 (R2TP) complex for the protein stabili...

Descripción completa

Detalles Bibliográficos
Autores principales: Goto, Greicy H., Ogi, Hiroo, Biswas, Himadri, Ghosh, Avik, Tanaka, Seiji, Sugimoto, Katsunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578694/
https://www.ncbi.nlm.nih.gov/pubmed/28827813
http://dx.doi.org/10.1371/journal.pgen.1006873

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578694/
https://www.ncbi.nlm.nih.gov/pubmed/28827813
http://dx.doi.org/10.1371/journal.pgen.1006873

Ejemplares similares