Principles of cellular resource allocation revealed by condition-dependent proteome profiling

Growing cells coordinate protein translation with metabolic rates. Central to this coordination is ribosome production. Ribosomes drive cell growth, but translation of ribosomal proteins competes with production of non-ribosomal proteins. Theory shows that cell growth is maximized when all expressed...

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Detalles Bibliográficos
Autores principales: Metzl-Raz, Eyal, Kafri, Moshe, Yaakov, Gilad, Soifer, Ilya, Gurvich, Yonat, Barkai, Naama
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578734/
https://www.ncbi.nlm.nih.gov/pubmed/28857745
http://dx.doi.org/10.7554/eLife.28034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578734/
https://www.ncbi.nlm.nih.gov/pubmed/28857745
http://dx.doi.org/10.7554/eLife.28034

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