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Principles of cellular resource allocation revealed by condition-dependent proteome profiling
Growing cells coordinate protein translation with metabolic rates. Central to this coordination is ribosome production. Ribosomes drive cell growth, but translation of ribosomal proteins competes with production of non-ribosomal proteins. Theory shows that cell growth is maximized when all expressed...
Autores principales: | Metzl-Raz, Eyal, Kafri, Moshe, Yaakov, Gilad, Soifer, Ilya, Gurvich, Yonat, Barkai, Naama |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578734/ https://www.ncbi.nlm.nih.gov/pubmed/28857745 http://dx.doi.org/10.7554/eLife.28034 |
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