Cation selectivity of the presequence translocase channel Tim23 is crucial for efficient protein import

Virtually all mitochondrial matrix proteins and a considerable number of inner membrane proteins carry a positively charged, N-terminal presequence and are imported by the TIM23 complex (presequence translocase) located in the inner mitochondrial membrane. The voltage-regulated Tim23 channel constit...

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Detalles Bibliográficos
Autores principales: Denkert, Niels, Schendzielorz, Alexander Benjamin, Barbot, Mariam, Versemann, Lennart, Richter, Frank, Rehling, Peter, Meinecke, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578737/
https://www.ncbi.nlm.nih.gov/pubmed/28857742
http://dx.doi.org/10.7554/eLife.28324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578737/
https://www.ncbi.nlm.nih.gov/pubmed/28857742
http://dx.doi.org/10.7554/eLife.28324

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