Hippocampal Perineuronal Nets Are Required for the Sustained Antidepressant Effect of Ketamine

BACKGROUND: N-methyl-D-aspartate receptor antagonists, like ketamine, produce a rapid-acting and long-lasting antidepressant effect. Although the mechanism is not completely understood, ketamine is thought to preferentially target N-methyl-D-aspartate receptors on fast-spiking parvalbumin-containing...

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Detalles Bibliográficos
Autores principales: Donegan, Jennifer J, Lodge, Daniel J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578802/
https://www.ncbi.nlm.nih.gov/pubmed/27806991
http://dx.doi.org/10.1093/ijnp/pyw095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578802/
https://www.ncbi.nlm.nih.gov/pubmed/27806991
http://dx.doi.org/10.1093/ijnp/pyw095

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