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Hippocampal Perineuronal Nets Are Required for the Sustained Antidepressant Effect of Ketamine
BACKGROUND: N-methyl-D-aspartate receptor antagonists, like ketamine, produce a rapid-acting and long-lasting antidepressant effect. Although the mechanism is not completely understood, ketamine is thought to preferentially target N-methyl-D-aspartate receptors on fast-spiking parvalbumin-containing...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578802/ https://www.ncbi.nlm.nih.gov/pubmed/27806991 http://dx.doi.org/10.1093/ijnp/pyw095 |