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INTU is essential for oncogenic Hh signaling through regulating primary cilia formation in basal cell carcinoma (BCC)

Inturned (INTU), a cilia and planar polarity effector (CPLANE), performs prominent ciliogenic functions during morphogenesis, such as in the skin. INTU is expressed in adult tissues but its role in tissue maintenance is unknown. Here, we report that the expression of the INTU gene is aberrantly elev...

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Detalles Bibliográficos
Autores principales: Yang, Ning, Leung, Elaine Lai-Han, Liu, Chengbao, Li, Li, Eguether, Thibaut, Yao, Xiao Jun, Jones, Evan C., Norris, David A., Liu, Aimin, Clark, Richard A., Roop, Dennis R., Pazour, Gregory J., Shroyer, Kenneth R., Chen, Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578876/
https://www.ncbi.nlm.nih.gov/pubmed/28459465
http://dx.doi.org/10.1038/onc.2017.117