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INTU is essential for oncogenic Hh signaling through regulating primary cilia formation in basal cell carcinoma (BCC)
Inturned (INTU), a cilia and planar polarity effector (CPLANE), performs prominent ciliogenic functions during morphogenesis, such as in the skin. INTU is expressed in adult tissues but its role in tissue maintenance is unknown. Here, we report that the expression of the INTU gene is aberrantly elev...
Autores principales: | Yang, Ning, Leung, Elaine Lai-Han, Liu, Chengbao, Li, Li, Eguether, Thibaut, Yao, Xiao Jun, Jones, Evan C., Norris, David A., Liu, Aimin, Clark, Richard A., Roop, Dennis R., Pazour, Gregory J., Shroyer, Kenneth R., Chen, Jiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578876/ https://www.ncbi.nlm.nih.gov/pubmed/28459465 http://dx.doi.org/10.1038/onc.2017.117 |
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