Genome-wide DNA methylation profiling reveals cancer-associated changes within early colonic neoplasia

Colorectal cancer (CRC) is characterized by genome-wide alterations to DNA methylation that influence gene expression and genomic stability. Less is known about the extent to which methylation is disrupted in the earliest stages of CRC development. In this study we have combined laser-capture microd...

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Detalles Bibliográficos
Autores principales: Hanley, Matthew P., Hahn, Maria A., Li, Arthur X., Wu, Xiwei, Lin, Jianan, Wang, Jinhui, Choi, Audrey, Ouyang, Zhengqing, Fong, Yuman, Pfeifer, Gerd P., Devers, Thomas J., Rosenberg, Daniel W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578878/
https://www.ncbi.nlm.nih.gov/pubmed/28459462
http://dx.doi.org/10.1038/onc.2017.130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578878/
https://www.ncbi.nlm.nih.gov/pubmed/28459462
http://dx.doi.org/10.1038/onc.2017.130

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