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A regulated PNUTS mRNA to lncRNA splice switch mediates EMT and tumor progression

The contribution of lncRNAs to tumor progression and regulatory mechanisms driving their expression are areas of intense investigation. Here, we characterize the binding of heterogeneous nuclear ribonucleoprotein E1 (hnRNP E1) to a nucleic acid structural element located in exon 12 of PNUTS (also kn...

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Detalles Bibliográficos
Autores principales: Grelet, Simon, Link, Laura A., Howley, Breege, Obellianne, Clémence, Palanisamy, Viswanathan, Gangaraju, Vamsi K., Diehl, J. Alan, Howe, Philip H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578890/
https://www.ncbi.nlm.nih.gov/pubmed/28825698
http://dx.doi.org/10.1038/ncb3595