Genome-wide reconstruction of complex structural variants using read clouds

Microfluidic partitioning of long genomic DNA fragments, and barcoding of shorter fragments derived from them, retains long-range information in short sequencing reads. Such read cloud approaches represent a powerful and cost-effective alternative to single-molecule long-read sequencing. We develope...

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Detalles Bibliográficos
Autores principales: Spies, Noah, Weng, Ziming, Bishara, Alex, McDaniel, Jennifer, Catoe, David, Zook, Justin M., Salit, Marc, West, Robert B., Batzoglou, Serafim, Sidow, Arend
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578891/
https://www.ncbi.nlm.nih.gov/pubmed/28714986
http://dx.doi.org/10.1038/nmeth.4366

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578891/
https://www.ncbi.nlm.nih.gov/pubmed/28714986
http://dx.doi.org/10.1038/nmeth.4366

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