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Epigenetic Regulation of PLIN1 in Obese Women and its Relation to Lipolysis

Increased adipocyte lipolysis links obesity to insulin resistance. The lipid droplet coating-protein Perilipin participates in regulation of lipolysis and is implicated in obesity. In the present study we investigate epigenetic regulation of the PLIN1 gene by correlating PLIN1 CpG methylation to gen...

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Detalles Bibliográficos
Autores principales: Bialesova, Lucia, Kulyté, Agné, Petrus, Paul, Sinha, Indranil, Laurencikiene, Jurga, Zhao, Chunyan, Wright, Karin Dahlman, Arner, Peter, Dahlman, Ingrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578955/
https://www.ncbi.nlm.nih.gov/pubmed/28860604
http://dx.doi.org/10.1038/s41598-017-09232-y