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Deficiency of TLR4 homologue RP105 aggravates outward remodeling in a murine model of arteriovenous fistula failure

Arteriovenous access dysfunction is a major cause of morbidity for hemodialysis patients. The pathophysiology of arteriovenous fistula (AVF) maturation failure is associated with inflammation, impaired outward remodeling (OR) and intimal hyperplasia. RP105 is a critical physiologic regulator of TLR4...

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Detalles Bibliográficos
Autores principales: Bezhaeva, Taisiya, Wong, ChunYu, de Vries, Margreet R., van der Veer, Eric P., van Alem, Carla M. A., Que, Ivo, Lalai, Reshma A., van Zonneveld, Anton-Jan, Rotmans, Joris I., Quax, Paul H. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578984/
https://www.ncbi.nlm.nih.gov/pubmed/28860634
http://dx.doi.org/10.1038/s41598-017-10108-4