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Deficiency of TLR4 homologue RP105 aggravates outward remodeling in a murine model of arteriovenous fistula failure
Arteriovenous access dysfunction is a major cause of morbidity for hemodialysis patients. The pathophysiology of arteriovenous fistula (AVF) maturation failure is associated with inflammation, impaired outward remodeling (OR) and intimal hyperplasia. RP105 is a critical physiologic regulator of TLR4...
Autores principales: | Bezhaeva, Taisiya, Wong, ChunYu, de Vries, Margreet R., van der Veer, Eric P., van Alem, Carla M. A., Que, Ivo, Lalai, Reshma A., van Zonneveld, Anton-Jan, Rotmans, Joris I., Quax, Paul H. A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578984/ https://www.ncbi.nlm.nih.gov/pubmed/28860634 http://dx.doi.org/10.1038/s41598-017-10108-4 |
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