Cargando…

Prolonged AT(1)R activation induces Ca(V)1.2 channel internalization in rat cardiomyocytes

The cardiac L-type calcium channel is a multi-subunit complex that requires co-assembling of the pore-forming subunit Ca(V)1.2 with auxiliary subunits Ca(V)α(2)δ and Ca(V)β. Its traffic has been shown to be controlled by these subunits and by the activation of various G-protein coupled receptors (GP...

Descripción completa

Detalles Bibliográficos
Autores principales: Hermosilla, Tamara, Encina, Matías, Morales, Danna, Moreno, Cristian, Conejeros, Carolina, Alfaro-Valdés, Hilda M., Lagos-Meza, Felipe, Simon, Felipe, Altier, Christophe, Varela, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578992/
https://www.ncbi.nlm.nih.gov/pubmed/28860469
http://dx.doi.org/10.1038/s41598-017-10474-z