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Prolonged AT(1)R activation induces Ca(V)1.2 channel internalization in rat cardiomyocytes
The cardiac L-type calcium channel is a multi-subunit complex that requires co-assembling of the pore-forming subunit Ca(V)1.2 with auxiliary subunits Ca(V)α(2)δ and Ca(V)β. Its traffic has been shown to be controlled by these subunits and by the activation of various G-protein coupled receptors (GP...
Autores principales: | Hermosilla, Tamara, Encina, Matías, Morales, Danna, Moreno, Cristian, Conejeros, Carolina, Alfaro-Valdés, Hilda M., Lagos-Meza, Felipe, Simon, Felipe, Altier, Christophe, Varela, Diego |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578992/ https://www.ncbi.nlm.nih.gov/pubmed/28860469 http://dx.doi.org/10.1038/s41598-017-10474-z |
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