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Assessment of selected media supplements to improve F/HN lentiviral vector production yields

The development of lentiviral-based therapeutics is challenged by the high cost of current Good Manufacturing Practices (cGMP) production. Lentiviruses are enveloped viruses that capture a portion of the host cell membrane during budding, which then constitutes part of the virus particle. This proce...

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Detalles Bibliográficos
Autores principales: Gélinas, Jean-François, Davies, Lee A., Gill, Deborah R., Hyde, Stephen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579034/
https://www.ncbi.nlm.nih.gov/pubmed/28860488
http://dx.doi.org/10.1038/s41598-017-07893-3