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Assessment of selected media supplements to improve F/HN lentiviral vector production yields
The development of lentiviral-based therapeutics is challenged by the high cost of current Good Manufacturing Practices (cGMP) production. Lentiviruses are enveloped viruses that capture a portion of the host cell membrane during budding, which then constitutes part of the virus particle. This proce...
Autores principales: | Gélinas, Jean-François, Davies, Lee A., Gill, Deborah R., Hyde, Stephen C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579034/ https://www.ncbi.nlm.nih.gov/pubmed/28860488 http://dx.doi.org/10.1038/s41598-017-07893-3 |
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