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Small molecule-based lineage switch of human adipose-derived stem cells into neural stem cells and functional GABAergic neurons

Cellular reprogramming using small molecules (SMs) without genetic modification provides a promising strategy for generating target cells for cell-based therapy. Human adipose-derived stem cells (hADSCs) are a desirable cell source for clinical application due to their self-renewal capacity, easy ob...

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Detalles Bibliográficos
Autores principales: Park, Jihye, Lee, Nayeon, Lee, Jaekwang, Choe, Eun Kyung, Kim, Min Kyung, Lee, Jeonghoon, Byun, Min Soo, Chon, Myong-Wuk, Kim, Seong Who, Lee, C. Justin, Kim, Ju Han, Kwon, Jun Soo, Chang, Mi-Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579051/
https://www.ncbi.nlm.nih.gov/pubmed/28860504
http://dx.doi.org/10.1038/s41598-017-10394-y