Prerequisites for the acquisition of mammalian pathogenicity by influenza A virus with a prototypic avian PB2 gene

The polymerase of avian influenza A virus (AIV) is a heterotrimer composed of PB2, PB1, and PA. PB2 plays a role in overcoming the host barrier; however, the genetic prerequisites for avian PB2 to acquire mammalian pathogenic mutations have not been well elucidated. Previously, we identified a proto...

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Detalles Bibliográficos
Autores principales: Lee, Chung-Young, An, Se-Hee, Kim, Ilhwan, Go, Du-Min, Kim, Dae-Yong, Choi, Jun-Gu, Lee, Youn-Jeong, Kim, Jae-Hong, Kwon, Hyuk-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579056/
https://www.ncbi.nlm.nih.gov/pubmed/28860593
http://dx.doi.org/10.1038/s41598-017-09560-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579056/
https://www.ncbi.nlm.nih.gov/pubmed/28860593
http://dx.doi.org/10.1038/s41598-017-09560-z

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