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Connecting the dots across time: reconstruction of single-cell signalling trajectories using time-stamped data

Single-cell responses are shaped by the geometry of signalling kinetic trajectories carved in a multidimensional space spanned by signalling protein abundances. It is, however, challenging to assay a large number (more than 3) of signalling species in live-cell imaging, which makes it difficult to p...

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Detalles Bibliográficos
Autores principales: Mukherjee, Sayak, Stewart, David, Stewart, William, Lanier, Lewis L., Das, Jayajit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579131/
https://www.ncbi.nlm.nih.gov/pubmed/28879015
http://dx.doi.org/10.1098/rsos.170811