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Connecting the dots across time: reconstruction of single-cell signalling trajectories using time-stamped data
Single-cell responses are shaped by the geometry of signalling kinetic trajectories carved in a multidimensional space spanned by signalling protein abundances. It is, however, challenging to assay a large number (more than 3) of signalling species in live-cell imaging, which makes it difficult to p...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society Publishing
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579131/ https://www.ncbi.nlm.nih.gov/pubmed/28879015 http://dx.doi.org/10.1098/rsos.170811 |