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The stem cell regulator PEDF is dispensable for maintenance and function of hematopoietic stem cells

Pigment epithelium derived factor (PEDF), a ubiquitously expressed 50 kDa secreted glycoprotein, was recently discovered to regulate self-renewal of neural stem cells and have a supportive effect on human embryonic stem cell growth. Here, we analyzed expression of PEDF in the murine hematopoietic st...

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Detalles Bibliográficos
Autores principales: Rörby, Emma, Billing, Matilda, Dahl, Maria, Warsi, Sarah, Andradottir, Silja, Miharada, Kenichi, Siva, Kavitha, Jönsson, Jan-Ingvar, Blank, Ulrika, Karlsson, Göran, Karlsson, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579195/
https://www.ncbi.nlm.nih.gov/pubmed/28860613
http://dx.doi.org/10.1038/s41598-017-09452-2