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The stem cell regulator PEDF is dispensable for maintenance and function of hematopoietic stem cells
Pigment epithelium derived factor (PEDF), a ubiquitously expressed 50 kDa secreted glycoprotein, was recently discovered to regulate self-renewal of neural stem cells and have a supportive effect on human embryonic stem cell growth. Here, we analyzed expression of PEDF in the murine hematopoietic st...
Autores principales: | Rörby, Emma, Billing, Matilda, Dahl, Maria, Warsi, Sarah, Andradottir, Silja, Miharada, Kenichi, Siva, Kavitha, Jönsson, Jan-Ingvar, Blank, Ulrika, Karlsson, Göran, Karlsson, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579195/ https://www.ncbi.nlm.nih.gov/pubmed/28860613 http://dx.doi.org/10.1038/s41598-017-09452-2 |
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