A CDC42-centered signaling unit is a dominant positive regulator of endothelial integrity

Endothelial barrier function is carefully controlled to protect tissues from edema and damage inflicted by extravasated leukocytes. RhoGTPases, in conjunction with myriad regulatory proteins, exert both positive and negative effects on the endothelial barrier integrity. Precise knowledge about the r...

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Detalles Bibliográficos
Autores principales: Amado-Azevedo, J., Reinhard, N. R., van Bezu, J., de Menezes, R. X., van Beusechem, V. W., van Nieuw Amerongen, G. P., van Hinsbergh, V. W. M., Hordijk, P. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579287/
https://www.ncbi.nlm.nih.gov/pubmed/28860633
http://dx.doi.org/10.1038/s41598-017-10392-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579287/
https://www.ncbi.nlm.nih.gov/pubmed/28860633
http://dx.doi.org/10.1038/s41598-017-10392-0

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