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Control of box C/D snoRNP assembly by N(6)‐methylation of adenine

N(6)‐methyladenine is the most widespread mRNA modification. A subset of human box C/D snoRNA species have target GAC sequences that lead to formation of N(6)‐methyladenine at a key trans Hoogsteen‐sugar A·G base pair, of which half are methylated in vivo. The GAC target is conserved only in those t...

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Detalles Bibliográficos
Autores principales: Huang, Lin, Ashraf, Saira, Wang, Jia, Lilley, David MJ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579392/
https://www.ncbi.nlm.nih.gov/pubmed/28623187
http://dx.doi.org/10.15252/embr.201743967