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CCCTC-binding factor is essential to the maintenance and quiescence of hematopoietic stem cells in mice

Hematopoiesis involves a series of lineage differentiation programs initiated in hematopoietic stem cells (HSCs) found in bone marrow (BM). To ensure lifelong hematopoiesis, various molecular mechanisms are needed to maintain the HSC pool. CCCTC-binding factor (CTCF) is a DNA-binding, zinc-finger pr...

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Detalles Bibliográficos
Autores principales: Kim, Tae-Gyun, Kim, Sueun, Jung, Soyeon, Kim, Mikyoung, Yang, Bobae, Lee, Min-Geol, Kim, Hyoung-Pyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579513/
https://www.ncbi.nlm.nih.gov/pubmed/28857086
http://dx.doi.org/10.1038/emm.2017.124