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CCCTC-binding factor is essential to the maintenance and quiescence of hematopoietic stem cells in mice
Hematopoiesis involves a series of lineage differentiation programs initiated in hematopoietic stem cells (HSCs) found in bone marrow (BM). To ensure lifelong hematopoiesis, various molecular mechanisms are needed to maintain the HSC pool. CCCTC-binding factor (CTCF) is a DNA-binding, zinc-finger pr...
Autores principales: | Kim, Tae-Gyun, Kim, Sueun, Jung, Soyeon, Kim, Mikyoung, Yang, Bobae, Lee, Min-Geol, Kim, Hyoung-Pyo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579513/ https://www.ncbi.nlm.nih.gov/pubmed/28857086 http://dx.doi.org/10.1038/emm.2017.124 |
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