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Inhibitory Effect of Lycopene on Amyloid-β-Induced Apoptosis in Neuronal Cells
Alzheimer′s disease (AD) is a fatal neurodegenerative disease. Brain amyloid-β deposition is a crucial feature of AD, causing neuronal cell death by inducing oxidative damage. Reactive oxygen species (ROS) activate NF-κB, which induces expression of Nucling. Nucling is a pro-apoptotic factor recruit...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579676/ https://www.ncbi.nlm.nih.gov/pubmed/28813012 http://dx.doi.org/10.3390/nu9080883 |